Document Type
Thesis
Date of Award
1976
Abstract
The soluble phosphoproteins of the dentin have been isolated from the rabbit, cow, hog, and human. The phosphoproteins were purified by means of gel filtration and anion-exchange chromatography, and polyacrylamide gel electrophoresis. They all showed high levels of aspartic acid, serine, and phosphate which is bound as phosphoserine. The data do not clearly suggest that a dentin phosphoprotein exists in the fish. The phosphoprotein of dentin may be a high molecular weight aggregate of greater than 150,000 daltons.The phosphoproteins purified in this study compare reasonably to the majority of the soluble and insoluble phosphoproteins isolated by other investigators.The findings of this study suggest that similar phosphoproteins are found in almost all mineralizing dentin. When combined with other electron and light microscopic and radioautographic data, the data of this study suggest that the dentin phosphoproteins are involved in the mineralization process. Radioautography in conjunction with electron microscopy would help to further support this hypothesis.
Recommended Citation
Beegle, William Frederick, "A Species Comparative Study of the Soluble Phosphoproteins of Dentin." (1976). All ETDs from UAB. 7003.
https://digitalcommons.library.uab.edu/etd-collection/7003
Comments
MS - Master of Science/Master of Surgery; ProQuest publication number 31751923