All ETDs from UAB

Advisory Committee Chair

Ejvis Lamani

Advisory Committee Members

Terpsithea Christou

Amjad Javed

Chung H Kau

Document Type


Date of Award


Degree Name by School

Master of Dentistry (MDent) School of Dentistry


Tooth agenesis is one of the most common developmental anomalies in humans and is defined as the failure of tooth development or odontogenesis. Prevalence of non-syndromic tooth agenesis has a reported range of 1.6-36.5% and varies by gender, ethnicity, and location. While tooth agenesis is well studied, information within ethnic groups requires further investigation. In this study, dental records of 3033 patients of the UAB School of Dentistry were evaluated to identify and categorize missing teeth by ethnicity and gender. Data analysis was conducted with Chi-square or Fisher’s exact test, with a two-sided significance level of 0.05. An overall prevalence rate for patients with non-syndromic tooth agenesis was identified as 3.3%. Frequency rates of congenitally missing teeth varied by ethnicity for Caucasians (4.5%), Asians (3.2%), African Americans (2.9%), and Hispanics (1.7%) and a statistically significant association was observed (p=0.006). Prevalence of tooth agenesis in males compared to females was not significant, except in the Hispanic group which consisted only of males (p=0.002). Moreover, not only did the study find that Caucasians were more likely to have missing teeth, but also more likely to have agenesis of two or more teeth. Within the population, the study found that the most common missing teeth are maxillary lateral incisors followed by mandibular second premolars and maxillary second premolars. Overall, this iii study provides prevalence rates and categorization of missing teeth by gender and ethnicity that may be utilized in future studies pertaining to genetics, epidemiology, and the investigation of further associations of TA patients with cancer.

Available for download on Sunday, December 22, 2024

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