All ETDs from UAB

Advisory Committee Chair

Russell Griffin

Advisory Committee Members

Rachael Lee

Sadeep Shrestha

Document Type

Thesis

Date of Award

2022

Degree Name by School

Master of Science in Public Health (MSPH) School of Public Health

Abstract

The aim of this study was to assess the association between the coronavirus disease (COVID-19) and the odds of ventilator associated events (VAEs). Retrospective analysis on prospectively collected data from 11,307 patients admitted to the intensive care unit (ICU) at the University of Alabama at Birmingham hospital between January 2018 and June 2022 was used. Outcomes considered were Any VAE, IVAC/PVAP, PVAP and MDRO PVAP. Crude and adjusted logistic regression models were used to evaluate the association between COVID-19 and the outcome variables. When a patient has Prior COVID-19, the odds of getting any VAE during the delta period is 1.59 times higher compared to the alpha period (OR=1.587; 95% CI=1.167-2.158; P=0.003). The study also found that, The odds of getting an IVAC/PVAP during the delta period is 1.90 times higher compared to Pre-COVID (OR=1.898; 95% CI=1.457-2.474; P <.00001). COVID-19 was associated with an increase in patients getting VAEs in hospitalized settings.

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