All ETDs from UAB

Advisory Committee Chair

Chung How Kau

Advisory Committee Members

Randy Cron

Peter Waite

Yedeh Paul Ying

Document Type


Date of Award


Degree Name by School

Master of Science (MS) School of Dentistry


Introduction: The most common disease in pediatric rheumatology is juvenile idiopathic arthritis (JIA). JIA is considered to be an autoimmune disease with an onset before the age of 16. The temporal mandibular joint (TMJ) has been reported to be involved in up to 87% of patients with JIA. Even though much research has been conducted on JIA, limited research has studied to understand its effect on the condyle-fossa relationship and to evaluate resorption amount on condyle by using a scoring system. Aim: The purpose of this study was (1) to evaluate the anatomical features of the glenoid fossa, (2) to assess the anatomical features of the condylar head, (3) to evaluate the space between glenoid fossa and the condylar head. Methods: The present retrospective cross-sectional study included Cone Beam CT (CBCT) images obtained from the sagittal, coronal, and axial slices. In the multidisciplinary Pediatric Rheumatology Outpatient Clinic at The University of Alabama at Birmingham (UAB) children with JIA are also examined by a group of orthodontists working in the same institute from October 2018 to July 2019. The predictor variable consists of patients with JIA and without JIA. The primary outcome variables are the depth of the mandibular fossa, joint spaces, axial angles, medio-lateral width, and condyle resorption. Other study iv variables were age and sex. In this study, the measurements obtained from two different groups (with JIA and without JIA) are compared using a t-test, where Tukey is utilized to adjust for multiple comparisons. The left and right joints are analyzed separately as the paired t-test conducted showed a significant difference between the two joints (p < 0.05). Results: The study was comprised of 34 patients diagnosed with JIA and 34 healthy subjects. The depth of the mandibular fossa, the anterior joint spaces, the axial angles, and the resorption index showed statistically significant differences between the JIA and healthy groups in both left and right sides (P<.05). However, there was no statistically significant difference in the posterior joint spaces and mediolateral width between JIA and healthy groups in both sides (P>.05). Conclusions: The results of our study presented the destructive potential of juvenile idiopathic arthritis by using CBCT. CBCT scanning is a helpful tool in the evaluation of the radiographic result of TMJ.

Included in

Dentistry Commons



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