Heersink School of Medicine ETDs

Heersink School of Medicine ETDs

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2016

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Exploring Bacteriophage P22 As A Selective Molecular Scaffold And Molecular Sensor, Gregory Joseph Bedwell

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Structure-Function Relationships In The Sec7 Guanine Nucleotide Exchange Factor Gbf1, Jay Manoj Bhatt

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Behavioral and developmental abnormalities in SULT4A1 deficient zebrafish, Francis Crittenden

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HIV-1 adaptation to T-cell responses during infection, Victor Yimin Du

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The role of glutamate in immune cell infiltration and excitotoxic mechanisms in autoimmune demyelination, Kirsten Scarlett Evonuk

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Epigenetic Dysregulation in Levodopa-Induced Dyskinesia, David Anthony Figge

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Novel Biomarkers for Parkinson Disease, Kyle Bradley Fraser

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Copper Chaperone In Streptococcus Mutans Biofilm Formation And Dispersion Of Biofilms By Small Molecules, Sandra Stephanie Garcia

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Neurobiological Consequences of Perinatal SSRI Exposure, Matthew Edward Glover

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Examination of 4-hydroxy tamoxifen- and BH3 mimetic-induced cell death pathways in glioblastoma and malignant peripheral nerve sheath tumor cells, Christopher Dillon Graham

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Genome-Wide Transcription And Dna Methylation Profiling In An App Mouse Model Of Alzheimer’S Disease, Mikael C. Guzman Karlsson

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The Role Of Hydrogen Peroxide In The Modulation Of Capsule Biosynthesis In Streptococcus Pneumoniae Serotype 2, Jocelyn Renee Hauser

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Genetic Enhancer Screen With Transition Zone Mutant Nphp-4 Reveals Novel Interactions With Mutation Affecting Intraflagellar Transport And Endocytic Pathways, Scott Henke

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What's up, Dut? Help, help I'm being derepressed; the great derepression of SaPIs or how I learned to stop worrying and love mobilization, Rosanne Lorin Lee Hill

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The effect of proinflammatory cytokines on thioredoxin-interacting protein in pancreatic beta-cells, Kyunghee Hong

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Motor unit remodeling during neuromuscular degeneration in aging and Parkinson's disease, Neil Anthony Kelly

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Impairment Of The Gliovascular Unit In Neurological Disease, Ian Kimbrough

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The Matricellular Protein Ccn1 Potentiates Fibrogenic Responses To Lung Injury, Ashish Kurundkar

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14-3-3 Proteins Regulate Mutant Lrrk2 Kinase Activity And Neurite Shortening, Nicholas Lavalley

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Leukemia Stem Cell Markers And Inv(16) In Acute Myeloid Leukemia, Jason Legrand

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Regulation of Breast Cancer Metastasis by SIN3 Chromatin Remodeling Complexes, Monica Jeanene Lewis

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Analysis Of The Ciliary Genes Gas8 And Mks6 Reveal Conserved Roles In Cilia Motility And Transition Zone Function, Wesley Robert Lewis

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Development Of A Split Luciferase Complementation Assay To Investigate Growth Hormone Receptor/ Prolactin Receptor Homo-/ Hetero-Association, Ying Liu

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Structural And Biochemical Charactereization Of Lrrk2, Zhiyong Liu

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Atp6v1c1 Enhances Breast Cancer Growth by Activating V-ATPase mediated mTORC1 Signaling and Metastasis by Increasing V-ATPase Activity in Cancer Cells, Matthew J. McConnell

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Neurodevelopmental alterations in a rodent model of temperamental differences, Chelsea Mccoy McCoy

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Cell-Specific PGC-1α-Dependent Transcription: Implications for Cognitive and Motor Dysfunction, Laura McMeekin

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Transcriptional Regulation of Interleukin 10 in CD4+ T Cells, Carson Edward Moseley

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Ribosomal Protein L12 (Rpl12) as a Novel Target in Cystic Fibrosis, Kathryn E. Oliver

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Targeting the tumor-promoting microenvironment with inhibitors of pro-HGF activation, Benjamin Yaw Owusu

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Neonatal Microbial Exposure And Its Effects On The B Cell Repertoire And Development Of Respiratory Allergies, Preeyam Patel

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Early-life Programming of Emotional Behaviors and Cardiovascular Function, Samir Rana

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Reorganization of the Golgi Apparatus During Human Cytomegalovirus Infection, George Michael Rebmann

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CD4 Regulatory T Cells Augment HIV-1 Expression of Polarized M1 and M2 Monocyte Derived Macrophages, Tanya Robinson

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Altering Metabolism In The Tumor Microenvironment To Enhance Anti-Tumor Immunity For Lung Cancer, Cara Schafer

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Regulation of the Mitochondrial Thiol Network with Targeted Electrohpiles, Matthew Ryan Smith

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The Role of Mammalian Tribbles Homolog 3 (TRB3) in Macrophage Biology; Evidence for Reciprocal Regulation of Macrophage Function in Foam Cell Formation, Dennis Steverson

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The Function Of Prmt1 In Normal And Abnormal Megakaryopoiesis, Hairui Su

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Microglia Orchestrate The Inflammatory Response To Alpha-Synuclein In Parkinson Disease Models, Aaron Thome

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The Roles Of Il-21 And Il-10 In Cellular And Humoral Immune Responses, Yuan Tian

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Human Cytosolic Sulfotransferase (Sult) 1B1 Half-Site Reactivity And The Identification And Characterization Of A Novel Variant Sult1B1 Isoform (L145V), Zachary Evan Tibbs

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Polycomb Repressive Complex 2 and Heterochromatin Protein 1 Beta Regulate Neural and Neural Crest Development, Chih-Liang Tien

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Germline Restriction Of B Cell Receptor Repertoire Influences Antigenic Epitope Recognition And Primary Antibody Deficiency Pathogenesis, Yuge Wang

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Cell Signaling Pathways As Targets For Precision Medicine In Head And Neck Squamous Cell Carcinoma, Alice Weaver

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Interplay Between Her2, Parp1, And Nf-Κb In Breast Cancer: Potential Therapeutic Implications, Monicka Ewa Wielgos

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The Impact of rRNA and tRNA Synthesis on Chromatin Structure and Cell Fate, Jessica Makofske Woolnough

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Glycosyltransferases Involved In The Glycosylation Of Serine-Rich Glycoproteins From Streptococci, Fan Zhu

Theses/Dissertations from 2015

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The Regulation of Vitamin A Metabolism, Mark Adams

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Competition From New Neurons Drives Circuit Refinement In The Adult Dentate Gyrus, Elena W. Adlaf

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Pathophysiology And Metabolic Dysfunction Following Polytrauma, Robert Mackay Akscyn