Heersink School of Medicine ETDs

Heersink School of Medicine ETDs

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2024

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The Impact Of O-Glcnac Signaling On Dna Hydroxymethylation In Temporal Lobe Epilepsy, Rudhab Bahabry

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Phosphate Drives Pulmonary Inflammation Through Fgfr1, Erk, And Akt Signaling, Seth Bollenbecker

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Novel Roles Of Rab35 In Development And Disease, Kelsey Ruth Clearman

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The Multifaceted Role Of Neutrophil Heterogeneity In Covid-19 Pathogenesis, Marcus Darrell Davis

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The Role Of Fibroblast Growth Factor Receptors In Inflammatory Airway Diseases, Molly Easter

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Oncolytic Viral Therapy Reshapes The Anti-Glioma Cd4 T Cell Response And Their Tcr Repertoire, Jeffrey Grimes

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The Modification Of Single Domain Antibody Framework And Variable Regions To Impart Novel Pharmacodynamic And Pharmacokinetic Properties, Lucinda Ann Hall

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Diagnostic Imaging Approaches: Pet Imaging In Monitoring Immune Responses In Oncology And Tuberculosis, Chanelle Hunter

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Investigating Hiv-1 Transmission To Human Cervix Using Reporter Virus Technologies, Dana Frances Indihar

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Unmasking Molecular Mechanisms Of Multiple Maladies Through Multiomic Methodologies, Luke Potter

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Investigating The Electrostatics Of Mucins As Key Contributors To Mucus Stasis In Cystic Fibrosis, Elex Skylar Rose

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Catecholamines And Catecholamine Resistance In Animal Models Of Metabolic Syndrome, Robert Follett Rosencrans

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Non-Catalytic Regulators Of The Secretory Pathway, Peyton VanWinkle

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Associations Between Grit, Life Satisfaction, And Academic Outcomes In Elementary And Middle School Students, Charles Jaylon Williams

Theses/Dissertations from 2023

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Epigenetic Aberrations in Systemic Sclerosis and Systemic Lupus Erythematosus, Peter C. Allen

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Macrophage IPLA2ß-Derived Lipid Signaling Contributes to Type 1 Diabetes Development, Abdulaziz Saad Almutairi

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Characterizing a Unique OPRM1 Expressing Neuronal Population in the Rat Nucleus Accumbens, Emma Andraka

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Dact1, The “Super-Crosslinker”: Regulation Of Non-Canonical Wnt Signaling During Vertebrate Convergent Extension By Modulating Dishevelled Oligomerization, Allyson Angermeier

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Sialylation of Epidermal Growth Factor Receptor by the Sialyltransferase ST6GAL1 Modulates Receptor Activity and Downstream Signaling, Katherine Ankenbauer

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Crucial Role Of T Follicular Helper Cell-Derived Ifn-Γ In Lung Resident Memory B Cell Responses, Nicole Michelle Arroyo-Diaz

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Pharmacologic Proteasome Activators Ameliorate Alzheimer's-Like Pathology in Ad Fly Models, Mehar Bano

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Impact of Streptococcus Parasanguinis-Generated Reactive Nitrogen Species on Pseudomonas Aeruginosa Virulence and the Host Response, Joshua J. Baty

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Uncovering the Role of SPT5 in RNA Polymerase I Transcription Through Targeted Protein Degradation Via the Auxin Inducible Degron System in Saccharomyces Cerevisiae, Nathan Bellis

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Chronic Circadian Disruption Increases Risk for Cardiovascular Disease, Jazmine I Benjamin

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Novel role for ST6Gal1 sialyltransferase as a tumor driver in pancreatic ductal adenocarcinoma, Nikita Umakant Bhalerao

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Regulatory Elements of Polyphosphate Biosynthesis, Marvin Qortez Bowlin

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Reduction of Sphingomyelinases Associated with Progranulin Deficiency and Frontotemporal Dementia, Nicholas R. Boyle

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Investigation into the Structure and Function of Tyrosyl-DNA Phosphodiesterase I's N-Terminal Domain, Evan J. Brettrager

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Modular Regulation and Function of the Polypyrimidine Tract Binding Protein 1 (PTBP1), Christine Carico

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Role Of Proteoglycan Forms Of The Type Iii Tgf-Β Receptor/Betaglycan In Tgf-Β Signaling In Ovarian Cancer Models, Alex Kwon-Bowers Choi

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Impact of Arthroplasty Surgery on the Local Immune Composition of the Knee Joint and Implications for the Periprosthetic Joint Infection, Kyle H. Cichos

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Neutrophil Heterogeneity and Alternative Granulopoiesis in Chronic Inflammatory Conditions, Ashley N. Connelly

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Strategies for HER2 Targeted PET Imaging, Maxwell Adams Ducharme

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Spatial/Temporal Zonation, Diversification, and Evolutionary Conservation of Kidney Resident Macrophage Subpopulations in Mice and Humans After Kidney Injury, Elise Nicole Erman

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Challenges and Opportunities in Glioblastoma and Immunovirotherapy with Oncolytic Herpes Simplex Virus Type 1, Dagoberto Estevez-Ordonez

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Application of Machine Learning and Network Approaches to Prioritize Safe and Efficacious Drug Repurposing Candidates, Jennifer L. Fisher

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Differential Mechanisms of Intestinal Inflammation Drive Pathogenesis of Diabetic Retinopathy in Type 1 and Type 2 Diabetes, Jason Levi Floyd

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Molecular Influences of Racial Disparities in Pancreatic Neuroendocrine Tumors, Brendon Herring

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Molecular Determinants of Retroviral Gag Targeting to the Plasma Membrane for Assembly, Dominik Herrmann

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Unveiling the Molecular Features of Cancer Health Differences Through Multi-Omics Data Analysis, Fengyuan Huang

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Investigating Regulatory Mechanisms of Transcription by RNA Polymerase I, Abigail Kate Huffines

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The Long Non-Coding RNA NEAT1 Mediates Astrocyte Gene Expression and Hippocampus-Dependent Memory in Aging and Alzheimer's Disease, Ashleigh Burns Irwin

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Biochemical Characterization of RNA Polymerases I, II, and III and Its Therapeutic Implications, Ruth Qian Jacobs

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Understanding Molecular Mechanisms of Glioblastoama Resistance to Design Novel Combinatorial Therapies, Amber B. Jones

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Impact Of Exercise On Antioxidative-Stress Induced Endoplasmic Reticulum Dysfunction And Cardiac Remodelling, Arun Jyothidasan

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Optimization of Progranulin Gene Therapy, a Potential Treatment for Frontotemporal Dementia, Shreya Natesh Kashyap

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The Critical Period Of Long-Term Plasticity In Adult-Born Granule Cells Is Mediated By T-Type Calcium Channels, William Michael Kennedy

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The Molecular and Structural Basis of B Cell Epitope Targeting in Transplant Rejection, John T. Killian Jr

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Characterizing The Role Of Mapk Phosphatases In Age-Dependent Macrophage Dysfucntion And Increased Suceptiblity To Pneumonia In A Tnf-Dependent Manner, Katherine Lauren Kruckow

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Plasticity Characteristics of CXCR5+ CD4+ T Memory Cells and CXCR5- Non-TFH Memory Cells, Ching-En Lee