ETDs from Heersink School of Medicine

ETDs from Heersink School of Medicine

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2019

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Receptor Sialylation By St6Gal-I Promotes Tumor Progression By Enhancing Tumor Cell Survival And Epithelial To Mesenchymal Transition, Colleen Maeve Britain

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The Impact Of Redox Stress In Primary Hyperoxaluria Type 1, Brianna Buchalski

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Context Fear Memory Formation Is Regulated By Hippocampal Lncrna-Mediated Histone Methylation Changes, Anderson Alan Butler

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St6Gal-I Mediated Sialylation Promotes Pancreatic Ductal Adenocarcinoma Progression And Chemoresistance, Asmi Chakraborty

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DNA Template Sequence Effects on RNA Polymerase I Transcription Elongation, Andrew Martin Clarke

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Regulation Of St6Gal-I In Cancer: Sox2 Identified As Novel Driver Of St6Gal-I Expression, Kaitlyn Alexandra Dorsett

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Regulation of Intestinal Innate Lymphoid Cells in Acute and Chronic Inflammation, Sarah Dulson

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Marcks Effector Domain: Functions In Glioblastoma Progression And Novel Cytolytic Therapy, Nicholas James Eustace

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BET Bromodomain Inhibition as an Approach for Treatment of Cholangiocarcinoma, Samuel Charles Fehling

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Identification Of Two Spop-Mediated Pathways In Prostate Cancer Progression, Joshua Fried

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BAF Chromatin Landscaping During Bone Formation and Maintenance, Tanner Cole Godfrey

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Characterizing the HIV-1 Envelope N-glycan Shield, Audra Ann Hargett

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Investigating The Rho-Kinase (Rock) Signaling Pathway As A Therapeutic Target In Alzheimer’S Disease, Benjamin Wade Henderson

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Bdnf/Trkb.T1 Signaling: A Novel Mechanism Of Astrocyte Morphological Maturation, Leanne Holt

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Exosomal Transfer of Mitochondrial and T Cell Activation as a Novel Mechanism of TH2 and TH17 Polarization in Asthma, Kenneth Hough

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Characterization of the TGFb pathway and its role in prostaglandin metabolism in C. elegans, Muhan Hu

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The Role Of The St6Gal-I Sialyltrasferase In Protecting Tumor Cells From Hypoxic Stress, Robert Brent Jones

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Structural and Functional Insights into Influenza A Virus NS1-Mediated RIG-I Antagonism, Alexander Jureka

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Bk Polyomavirus Activates The Dna Damage Response To Hijack Host Cell Cycle Control, Joshua L. Justice

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The Electronic Health Record and the Clinical Informatics Researcher: A Journey to Predicting False Positive Alerts with Patient Characteristics, Timothy Kennell

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Structural And Functional Insights Into The Influenza A Virus Non-Structural Protein 1 Effector Domain, Alex Kleinpeter

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A Structure Based Approach For Defining Ligand Interaction Requirements With Atp-Binding Cassette Proteins, Christina A. Le

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Kidney Resident Macrophages Utilize Developmental Programming During Healing From Acute Kidney Injury, Jeremie Matthew Peabody Lever

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Structural Studies Of Some Proteins Responsible For Bacterial Pathogenesis, Kartik Manne

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Appropriately timed epigenetic manipulation with histone deacetylase inhibitors as a platform approach to tumor immunotherapy, Tyler McCaw

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Endothelial N-Glycan Hypoglycosylation Enhances Cd16+ Monocyte Adhesion: A Role For Alpha-Mannosidases, Kellie Regal McDonald

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Structural And Biophysical Investigations Into The Mechanism Of Hiv-1 Envelope Incorporation, Richard Elliot Murphy

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Ribosomal Rna Synthesis Is Regulated By Pathways That Respond To Environmental And Stress Conditions, Saman Najmi

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Genome Sequencing To Identify Novel Developmental Disorder Variation, Matthew Neu

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Early Life Stress and Immune Responses in Adult Rat Kidneys, Ijeoma E. Obi

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Ventral Hippocampal Input To The Medial Prefrontal Cortex Regulates Social Memory, Mary Leann Phillips

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The Reductive Stress Reducto-miR: Emerging Insight into microRNA-671, Justin Michael Quiles

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Determination of the role of SMU_833 in the fitness and virulence of cariogenic Streptococcus mutans, Katherine Lynn Rainey

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Pannexin 1 Channel Inhibition to Prevent Triggered Arrhythmia, Grace Elizabeth Salzer

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The Influence Of O-Glcnacylation On Dna 5-Hydroxymethylation In The Epileptic Hippocampus, Richard Gilbert Sanchez

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Integration of yeast phenomics and cancer pharmacogenomics to model precision medicine, Sean Santos

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Transcriptional dynamics of dopaminergic signaling, Katherine Elizabeth Savell

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Targeting The Nad Salvage Pathway For The Treatment Of The Parasitic Disease Schistosomiasis, Michael David Schultz

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Novel Approaches To Enhance Translational Readthrough Efficacy For Cystic Fibrosis Nonsense Mutations, Jyoti Sharma

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Characterization of Chemical Uptake and Aryl Hydrocarbon Receptor Mutations in Zebrafish, Jaclyn Paige Souder

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Dysregulation In The Central Nervous System Upon Mcmv Infection In Newborn Mice, Cathy Yea Won Sung

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Therapeutic Mechanisms in Sickle Cell Nephropathy, Crystal Taylor

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Acetylcholine signaling in glioblastoma invasion and peritumoral hyperexcitability, Emily Grace Thompson

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Modulation of Klotho Affects Dendritic Spine Remodeling and Neuronal Network Activity, Hai T. Vo

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The Anti-Tumor Effects Of Hur Inhibition In Glioblastoma, Jiping Wang

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Novel Biomarkers For Parkinson Disease, Shijie Wang

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Using Peptide Mimetics To Probe Protein-Protein Interactions Significant In Cancers, Robert H. Whitaker

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The Role of Protein O-GlcNAcylation in Regulating Mitochondrial Function, Jalessa Nicole Wright

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The Role Of Suppressor Of Cytokine Signaling 3 In Neuroinflammatory Disease, Zhaoqi Yan

Theses/Dissertations from 2018

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Mechanisms Of Leucine-Rich Repeat Kinase 2 And Alphα-Synuclein In Pathogenesis Of Parkinson Disease, Hisham Abdelmotilib