Heersink School of Medicine ETDs

Heersink School of Medicine ETDs

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2019

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BAF Chromatin Landscaping During Bone Formation and Maintenance, Tanner Cole Godfrey

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Characterizing the HIV-1 Envelope N-glycan Shield, Audra Ann Hargett

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Investigating The Rho-Kinase (Rock) Signaling Pathway As A Therapeutic Target In Alzheimer’S Disease, Benjamin Wade Henderson

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Bdnf/Trkb.T1 Signaling: A Novel Mechanism Of Astrocyte Morphological Maturation, Leanne Holt

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Exosomal Transfer of Mitochondrial and T Cell Activation as a Novel Mechanism of TH2 and TH17 Polarization in Asthma, Kenneth Hough

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Characterization of the TGFb pathway and its role in prostaglandin metabolism in C. elegans, Muhan Hu

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The Role Of The St6Gal-I Sialyltrasferase In Protecting Tumor Cells From Hypoxic Stress, Robert Brent Jones

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Structural and Functional Insights into Influenza A Virus NS1-Mediated RIG-I Antagonism, Alexander Jureka

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Bk Polyomavirus Activates The Dna Damage Response To Hijack Host Cell Cycle Control, Joshua L. Justice

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The Electronic Health Record and the Clinical Informatics Researcher: A Journey to Predicting False Positive Alerts with Patient Characteristics, Timothy Kennell

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Structural And Functional Insights Into The Influenza A Virus Non-Structural Protein 1 Effector Domain, Alex Kleinpeter

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A Structure Based Approach For Defining Ligand Interaction Requirements With Atp-Binding Cassette Proteins, Christina A. Le

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Kidney Resident Macrophages Utilize Developmental Programming During Healing From Acute Kidney Injury, Jeremie Matthew Peabody Lever

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Structural Studies Of Some Proteins Responsible For Bacterial Pathogenesis, Kartik Manne

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Appropriately timed epigenetic manipulation with histone deacetylase inhibitors as a platform approach to tumor immunotherapy, Tyler McCaw

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Endothelial N-Glycan Hypoglycosylation Enhances Cd16+ Monocyte Adhesion: A Role For Alpha-Mannosidases, Kellie Regal McDonald

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Ribosomal Rna Synthesis Is Regulated By Pathways That Respond To Environmental And Stress Conditions, Saman Najmi

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Genome Sequencing To Identify Novel Developmental Disorder Variation, Matthew Neu

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Early Life Stress and Immune Responses in Adult Rat Kidneys, Ijeoma E. Obi

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Ventral Hippocampal Input To The Medial Prefrontal Cortex Regulates Social Memory, Mary Leann Phillips

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The Reductive Stress Reducto-miR: Emerging Insight into microRNA-671, Justin Michael Quiles

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Determination of the role of SMU_833 in the fitness and virulence of cariogenic Streptococcus mutans, Katherine Lynn Rainey

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Pannexin 1 Channel Inhibition to Prevent Triggered Arrhythmia, Grace Elizabeth Salzer

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The Influence Of O-Glcnacylation On Dna 5-Hydroxymethylation In The Epileptic Hippocampus, Richard Gilbert Sanchez

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Integration of yeast phenomics and cancer pharmacogenomics to model precision medicine, Sean Santos

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Transcriptional dynamics of dopaminergic signaling, Katherine Elizabeth Savell

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Targeting The Nad Salvage Pathway For The Treatment Of The Parasitic Disease Schistosomiasis, Michael David Schultz

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Intracellular Compartment-Specific Abnormalities In Proteasome Expression And Activity In The Superior Temporal Gyrus In Schizophrenia, Madeline R. Scott

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Novel Approaches To Enhance Translational Readthrough Efficacy For Cystic Fibrosis Nonsense Mutations, Jyoti Sharma

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Characterization of Chemical Uptake and Aryl Hydrocarbon Receptor Mutations in Zebrafish, Jaclyn Paige Souder

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Dysregulation In The Central Nervous System Upon Mcmv Infection In Newborn Mice, Cathy Yea Won Sung

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Therapeutic Mechanisms in Sickle Cell Nephropathy, Crystal Taylor

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Acetylcholine signaling in glioblastoma invasion and peritumoral hyperexcitability, Emily Grace Thompson

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Modulation of Klotho Affects Dendritic Spine Remodeling and Neuronal Network Activity, Hai T. Vo

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The Anti-Tumor Effects Of Hur Inhibition In Glioblastoma, Jiping Wang

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Novel Biomarkers For Parkinson Disease, Shijie Wang

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Using Peptide Mimetics To Probe Protein-Protein Interactions Significant In Cancers, Robert H. Whitaker

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The Role of Protein O-GlcNAcylation in Regulating Mitochondrial Function, Jalessa Nicole Wright

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The Role Of Suppressor Of Cytokine Signaling 3 In Neuroinflammatory Disease, Zhaoqi Yan

Theses/Dissertations from 2018

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Mechanisms Of Leucine-Rich Repeat Kinase 2 And Alphα-Synuclein In Pathogenesis Of Parkinson Disease, Hisham Abdelmotilib

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Collecting Duct NOS1 Activation is Necessary for Increased Glomerular Filtration Rate in Response to a High Salt Diet, John Miller Allan

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The Impact of the CD11b 77His and 1146Ser Variants on Mac-1 Activity and Functions, Justin Timothy Avery

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The Mechanism Of Tgf-Β Function In Development Of The Axial Skeleton, Ga I Ban

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Overcoming obesity-induced immunotherapeutic impairment, Shannon Boi

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Mitochondria-To-Nucleus Retrograde Signaling And Its Role In Cancer, Trevor Carden

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Mechanistic Connections Between Metabolic and Differentiation Programs in T Cells, Danielle Alexandria Chisolm

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Neuropeptide Y Cells Regulate Anxiety Behavior, Katelynn Corder

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Post-Transcriptional Regulation Of Myeloid Cell Leukemia 1 In Cancers, Jia Cui

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Cheminformatic Discovery And Characterization Of Copperdependent Bacterial Inhibitors, Alex Dalecki

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Functional analysis of Cdc45 in the replication fork and in response to replicative stress, Amanda Debrot