Heersink School of Medicine ETDs

Heersink School of Medicine ETDs

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2020

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Il-17 Producing Cd4 T Cells In Spontaneous Germinal Center And Autoantibody Formation In Murine Lupus, Huixian Hong

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C-reactive protein subverts the myeloid lineage: implications for renal injury, Rachel Jimenez

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Pharmacodynamic Responses And Efficacies Associated With Lrrk2 Inhibition, Kaela Kelly

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Elucidating The Role Of Hedgehog Signaling In Tumor Cell Response To Dna Damage And Microenvironmental Stress, Tshering Dolma Lama-Sherpa

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Locus Coeruleus Degeneration In Alzheimer’S Disease And Its Effect On Beta-Adrenergic Signaling In The Hippocampus, Bethany Langner

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Understanding And Targeting Glucose Transporter 3 In Glioblastoma, Catherine Jeanne Libby

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Protective Host Responses During Acute And Chronic Lung Exposure To Aspergillus Fumigatus, Joseph Mackel

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Gp44, A Minor Protein With A Major Role In Bacteriophage 80Α Infection, Keith Allen Manning

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Deficiency Of Tumor Suppressor Merlin Induces Metabolic Reprogramming In Breast Cancer, Mateus Mota

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Structural And Biophysical Investigations Into The Mechanism Of Hiv-1 Envelope Incorporation, Richard Elliot Murphy

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Downstream Pathways of Glucagon Receptor Agonism in Obesity, Shelly Nason

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Understanding The Impact Of Diet And Obesity On Anti-Tumor Immunity And Therapeutic Efficacy In Kidney Cancer, Rachael Miller Orlandella

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Disease Specific Dysregulation Of Stat1 And Stat5 Activation In Mature Cd4+ And Cd8+ T Cells Influences Enhanced Kinetic Responses And Inflammation In Patients With Treatment-Naïve Relapsing Remitting Multiple Sclerosis (Rrms), Brandon Jay Pope

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Novel Hiv Adaptation Strategy Against Host Cd8 T Cell Immunity, Kai Qin

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Investigating The Roles Of The Renal Primary Cilium Through The Use Of Intravital Imaging, Dustin Zachary Revell

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Noninvasive Neuromodulation Using A Benchtop Approach To Mri-Guided Focused Ultrasound Blood Brain Barrier Opening, Megan Rich

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Rna Polymerase I Elongation Kinetics: A Biochemical And Global Study Of A Cancer Therapeutic Target, Catherine Elizabeth Scull

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Novel Mechanisms of Nitric Oxide Activation in the Kidney, Randee Sedaka

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Diurnal dysfunction in control of sodium excretion in diet-induced obesity, Reham Soliman

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Mitochondrial Priming Of Tumor Initiating Cells Involves Repression Of Mitochondrial Fission Activity Towards Redox Regulation Of The Cell Cycle Regulator Cyclin E, Brian Spurlock

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Exploring The Roles Of Long Non-Coding Rnas In Glioblastoma Tumor Recurrence And Therapy Resistance, Christian Tyler Stackhouse

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Role Of Endogenous Tau In Lewy-Like Pathology, Lindsay Stoyka

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Toxin Secretion By Mycobacterium Tuberculosis, Uday Tak

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Contribution Of Adaptive Immune Responses In Chronic Lung Diseases, Thi Kim Tran-Nguyen

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Rab27 And 14-3-3 Mediated Regulation Of Alpha-Synuclein Pathology, Rachel Nicole Underwood

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Circadian Clock And Lipid Metabolism Disruption In Fatty Liver Disease, Jennifer Valcin

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Tau-Dependent Regulation Of Network Hyperexcitability By Alzheimer’S Disease Risk Gene Bin1, Yuliya Voskobiynyk

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Gene–Environment Interaction In Parkinson Disease: The Gut Microbiome, Zachary D. Wallen

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The Mir-23A Cluster Controls An Epigenetic Axis In Osteoblast Development During Bone Formation, Benjamin J. Wildman

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T cells in synucleinopathies, Gregory Paul Williams

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The Role of the Viral Envelope Protein gpUL132 in Assembly Compartment Formation and Virion Production: Intracellular Lipids and/or Cholesterol, Hui Wu

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Co-Factors In Fgf Signaling, Christopher Yanucil

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Network-based Analytics for Discovering Gene Modules and Biomarkers in Complex Diseases, Zongliang Yue

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Exploring The Mechanism Of Cleavage And Secretion Of The Major Sperm Protein (Msp) Domain Of The Vapb/Vpr-1 Protein, Hala Zein-Sabatto

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Circadian Control Of Blood Pressure And Renal Electrolyte Excretion, Dingguo Zhang

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Dopamine-dependent Transcriptional Dynamics in Striatal Physiology and Cocaine Reward, Morgan Elizabeth Zipperly

Theses/Dissertations from 2019

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O-Glcnac Regulation Of Inhibitory Circuits, Kavitha Abiraman

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Mechanisms of Acute Kidney Injury: The Role of Ferritin Heavy Chain in Renal Heme-unology, Laurence Marie Black

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Mechanisms of Acute Kidney Injury: The Role of Ferritin Heavy Chain in Renal Heme-unology, Laurence Marie Black

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The Role Of Nudc In Rod Photoreceptor Cell Maintenance: A New Function For An Old Protein, Evan Boitet

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Receptor Sialylation By St6Gal-I Promotes Tumor Progression By Enhancing Tumor Cell Survival And Epithelial To Mesenchymal Transition, Colleen Maeve Britain

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The Impact Of Redox Stress In Primary Hyperoxaluria Type 1, Brianna Buchalski

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Context Fear Memory Formation Is Regulated By Hippocampal Lncrna-Mediated Histone Methylation Changes, Anderson Alan Butler

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St6Gal-I Mediated Sialylation Promotes Pancreatic Ductal Adenocarcinoma Progression And Chemoresistance, Asmi Chakraborty

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DNA Template Sequence Effects on RNA Polymerase I Transcription Elongation, Andrew Martin Clarke

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Regulation Of St6Gal-I In Cancer: Sox2 Identified As Novel Driver Of St6Gal-I Expression, Kaitlyn Alexandra Dorsett

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Regulation of Intestinal Innate Lymphoid Cells in Acute and Chronic Inflammation, Sarah Dulson

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Marcks Effector Domain: Functions In Glioblastoma Progression And Novel Cytolytic Therapy, Nicholas James Eustace

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BET Bromodomain Inhibition as an Approach for Treatment of Cholangiocarcinoma, Samuel Charles Fehling

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Identification Of Two Spop-Mediated Pathways In Prostate Cancer Progression, Joshua Fried