ETDs from Heersink School of Medicine
Theses/Dissertations from 2024
Unmasking Molecular Mechanisms Of Multiple Maladies Through Multiomic Methodologies, Luke Potter
Catecholamines And Catecholamine Resistance In Animal Models Of Metabolic Syndrome, Robert Follett Rosencrans
The Role Of Altered Cell-Cell Communication Between Glia And Neurons In Alzheimer’S Disease, Tabea Marga Soelter
Non-Catalytic Regulators Of The Secretory Pathway, Peyton VanWinkle
Associations Between Grit, Life Satisfaction, And Academic Outcomes In Elementary And Middle School Students, Charles Jaylon Williams
Theses/Dissertations from 2023
Epigenetic Aberrations in Systemic Sclerosis and Systemic Lupus Erythematosus, Peter C. Allen
Macrophage IPLA2ß-Derived Lipid Signaling Contributes to Type 1 Diabetes Development, Abdulaziz Saad Almutairi
Characterizing a Unique OPRM1 Expressing Neuronal Population in the Rat Nucleus Accumbens, Emma Andraka
Induction of Antibiotic Activity Against Methicillin-Resistant Staphylococcus Aureus in Small Molecules Through Zinc Activation, Rachel Michaela Andrews
Dact1, The “Super-Crosslinker”: Regulation Of Non-Canonical Wnt Signaling During Vertebrate Convergent Extension By Modulating Dishevelled Oligomerization, Allyson Angermeier
Sialylation of Epidermal Growth Factor Receptor by the Sialyltransferase ST6GAL1 Modulates Receptor Activity and Downstream Signaling, Katherine Ankenbauer
Crucial Role Of T Follicular Helper Cell-Derived Ifn-Γ In Lung Resident Memory B Cell Responses, Nicole Michelle Arroyo-Diaz
Pharmacologic Proteasome Activators Ameliorate Alzheimer's-Like Pathology in Ad Fly Models, Mehar Bano
Impact of Streptococcus Parasanguinis-Generated Reactive Nitrogen Species on Pseudomonas Aeruginosa Virulence and the Host Response, Joshua J. Baty
Chronic Circadian Disruption Increases Risk for Cardiovascular Disease, Jazmine Benjamin
Novel role for ST6Gal1 sialyltransferase as a tumor driver in pancreatic ductal adenocarcinoma, Nikita Umakant Bhalerao
Regulatory Elements of Polyphosphate Biosynthesis, Marvin Qortez Bowlin
Reduction of Sphingomyelinases Associated with Progranulin Deficiency and Frontotemporal Dementia, Nicholas R. Boyle
Investigation into the Structure and Function of Tyrosyl-DNA Phosphodiesterase I's N-Terminal Domain, Evan J. Brettrager
Modular Regulation and Function of the Polypyrimidine Tract Binding Protein 1 (PTBP1), Christine Carico
Role Of Proteoglycan Forms Of The Type Iii Tgf-Β Receptor/Betaglycan In Tgf-Β Signaling In Ovarian Cancer Models, Alex Kwon-Bowers Choi
Impact of Arthroplasty Surgery on the Local Immune Composition of the Knee Joint and Implications for the Periprosthetic Joint Infection, Kyle H. Cichos
Neutrophil Heterogeneity and Alternative Granulopoiesis in Chronic Inflammatory Conditions, Ashley N. Connelly
Strategies for HER2 Targeted PET Imaging, Maxwell Adams Ducharme
Spatial/Temporal Zonation, Diversification, and Evolutionary Conservation of Kidney Resident Macrophage Subpopulations in Mice and Humans After Kidney Injury, Elise Nicole Erman
Challenges and Opportunities in Glioblastoma and Immunovirotherapy with Oncolytic Herpes Simplex Virus Type 1, Dagoberto Estevez-Ordonez
Application of Machine Learning and Network Approaches to Prioritize Safe and Efficacious Drug Repurposing Candidates, Jennifer L. Fisher
Molecular Influences of Racial Disparities in Pancreatic Neuroendocrine Tumors, Brendon Herring
Molecular Determinants of Retroviral Gag Targeting to the Plasma Membrane for Assembly, Dominik Herrmann
Unveiling the Molecular Features of Cancer Health Differences Through Multi-Omics Data Analysis, Fengyuan Huang
Investigating Regulatory Mechanisms of Transcription by RNA Polymerase I, Abigail Kate Huffines
The Long Non-Coding RNA NEAT1 Mediates Astrocyte Gene Expression and Hippocampus-Dependent Memory in Aging and Alzheimer's Disease, Ashleigh Burns Irwin
Biochemical Characterization of RNA Polymerases I, II, and III and Its Therapeutic Implications, Ruth Qian Jacobs
Understanding Molecular Mechanisms of Glioblastoama Resistance to Design Novel Combinatorial Therapies, Amber B. Jones
Impact Of Exercise On Antioxidative-Stress Induced Endoplasmic Reticulum Dysfunction And Cardiac Remodelling, Arun Jyothidasan
Optimization of Progranulin Gene Therapy, a Potential Treatment for Frontotemporal Dementia, Shreya Natesh Kashyap
The Critical Period Of Long-Term Plasticity In Adult-Born Granule Cells Is Mediated By T-Type Calcium Channels, William Michael Kennedy
The Molecular and Structural Basis of B Cell Epitope Targeting in Transplant Rejection, John T. Killian
Characterizing The Role Of Mapk Phosphatases In Age-Dependent Macrophage Dysfucntion And Increased Suceptiblity To Pneumonia In A Tnf-Dependent Manner, Katherine Lauren Kruckow
Plasticity Characteristics of CXCR5+ CD4+ T Memory Cells and CXCR5- Non-TFH Memory Cells, Ching-En Lee
Structural Characterization of Autoreactive IgG Fabs in the Context of IgA Nephropathy, Jordan Lingo
Time-Restricted Feeding Attenuates Obesity-Induced Muscle Dysfunction Through Energy Metabolism And Microbiota Modulation, Christopher Livelo
Time-Restricted Feeding Modulates Dgat2 Expression In Cardiac And Skeletal Muscle, Yiming Guo Livelo
Molecular imaging to evaluate tumor heterogeneity and guide treatment of breast cancer, Yun Lu
Molecular Mechanisms of Amphetamine Abuse, Samuel James Mabry
Investigating the Effects of Immune Checkpoint Inhibition and Combined Treatment with Evofosfamide on the Tumor Microenvironment Through Hypoxia Imaging, Kaytlyn Carter McNeal
Early Life Stress and Endothelin Receptor Type A: Separate Roles in Mediating Colitis, Rachel Q. Muir
Imaging Nanoscale Plasma Membrane Dynamics Reveals Diversity in Clathrin-Coated Vesicle Formation, Tomasz Jacek Nawara
Manipulation and Dependence on Host Cell Cycle by Human RNA and DNA Viruses: Human Coronavirus OC43 and BK Polyomavirus, Jason M. Needham