Heersink School of Medicine ETDs

Heersink School of Medicine ETDs

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2023

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Structural Characterization of Autoreactive IgG Fabs in the Context of IgA Nephropathy, Jordan Lingo

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Time-Restricted Feeding Attenuates Obesity-Induced Muscle Dysfunction Through Energy Metabolism And Microbiota Modulation, Chris Livelo

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Time-Restricted Feeding Modulates Dgat2 Expression In Cardiac And Skeletal Muscle, Yiming Guo Livelo

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Molecular imaging to evaluate tumor heterogeneity and guide treatment of breast cancer, Yun Lu

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Molecular Mechanisms of Amphetamine Abuse, Samuel James Mabry

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Investigating the Effects of Immune Checkpoint Inhibition and Combined Treatment with Evofosfamide on the Tumor Microenvironment Through Hypoxia Imaging, Kaytlyn Carter McNeal

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Early Life Stress and Endothelin Receptor Type A: Separate Roles in Mediating Colitis, Rachel Q. Muir

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Imaging Nanoscale Plasma Membrane Dynamics Reveals Diversity in Clathrin-Coated Vesicle Formation, Tomasz Jacek Nawara

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Manipulation and Dependence on Host Cell Cycle by Human RNA and DNA Viruses: Human Coronavirus OC43 and BK Polyomavirus, Jason M. Needham

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Chronic HIV Infection Influences the Immune Response to SARS-COV-2, Skye Opsteen

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Cd151+ T Cell Frequencies As An Immunological Clock That Identifies Premature Immunological Aging In People With Hiv, Mildred Perez

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A Tale of Two Waves: The Role of Genomic Enhancers in Regulating Transcriptional and Epigenetic Responses to Neuronal Activitiy, Robert A. Phillips III

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Understanding the Dual Role of the Oncolytic Viruses and Natural Killer Cells in Targeting Neuroblastoma, Colin Harrington Quinn

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T-BET Regulates the Maintenance and ASC Differentiation Potential of the Lymph Node and Lung Memory B Cell Compartments, Christopher A. Risley

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CIS-Regulatory Elements: Relevance for Alzheimer's Disease, Brianne Brazell Rogers

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Transcriptional Regulation in Early Stage CD4+ T Cell Activation and Differentiation, Andrew Ray Schroeder

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The Effects of Cannabidiol on Brain Temperature in Treatment-Resistant Epilepsy, Ayushe A. Sharma

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Expression of ST6GAL1 Imparts Stem-Like Cell Behaviors, Thereby Promoting Neoplasia, Sejal Sanjay Shinde

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Exercise-Driven Epigenetic and Transcriptomic Changes in an Experimental Model of Temporal Lobe Epilepsy, Silvienne C. Sint Jago

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The Influence Of Proximity On Patient Outcomes For Differently Structured Ambulatory Surgery Centers, Wendy Michelle Smith

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Interactions Between Pseudomonas Aeruginosa and the Oral Commensal Streptococcus Salivarius, Sara Noelle Stoner

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Sex-Stratified Genetic Analysis of Gout and Comorbidities, Nicholas Andrew Sumpter

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Neuropeptide Y Overexpression In The Presence Of P23H Rhodopsin Mutation, Jean Sun

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Aberrant Signal Transduction of Neuronal Injury: Trauma and Toxicology, Alan Umfress

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Investigating the p53 Tumor-Suppressive Network and the Dynamics/Mechanism of p53 Loss of Heterozygosity, Jun Wang

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Select Lipid Signaling. Derived From T-Cells Is An Important Contributor To Type 1 Diabetes Development, Tayleur White

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The Role of Tissue- and Cell-type-specific Expression and Regulation in SETBP1-associated Diseases, Jordan Hailey Whitlock

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Regulating Cancer Cell Metabolism During Hypoxia-Reoxygenation: Examing the Interplay of Gasotransmitters and Glutaminolysis, Dianna L. Xing

Theses/Dissertations from 2022

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Distinct Clinical Manifestations Associated with Autoantibodies and Cytokines in Systemic Lupus Erythematosus, Fatima K. Alduraibi

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Elucidating the Role of STAT4 in CD4 T Cell Mediated Pathogenicity, Ashlyn E. Anderson

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The Role of the Bone Marrow Microenvironment in FLT3-ITD Acute Myeloid Leukemia Stem Cell Resistance to FLT3 Inhibition, Nicholas R. Anderson

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Induction of Antibiotic Activity Against Methicillin-Resistant Staphylococcus Aureus in Small Molecules Through Zinc Activation, Rachel Michaela Andrews

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Molecular and Cellular Mechanisms of Resistance Training-Induced Skeletal Muscle Hypertrophic Response Heterogeneity in Older Adults, Margaret Bell

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NOX2-Derived Superoxide and MDA5-Dependant Responses Contribute to Autoimmune Diabetes, Samuel Isaac Blum

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Defining Genetic Underpinnings of Cellular Diversity and Vulnerability in the Context of Parkinson's Disease, Stephanie M. Boas

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The Role of Mitochondrial Genetic Background in Cellular Function, Response to Cell Stress and Disease Susceptability, Jamelle A. Brown

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IL-22 Mediated Host Defense During Attaching-Effacing Pathogen Infection, Baiyi Cai

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Grainyhead-Like 2 (GRHL2) Has Anti-Oncogenic Potential in Glioblastoma, Rachel M. Carnes

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Comprehensive Characterization of Structural Variations Using Long-Read Sequencing Data, Yu Chen

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The Role of Complement C3 in IgA Nephropathy, Sarah Elizabeth Coffee

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IL-2-Mediated STAT3 Activation Controls Effector T Regulatory Cell Development, Emma C. Dean

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Integrated Phenotypic and Molecular Expression Circuits in End-Stage Osteoarthritis, Devin J. Drummer

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Determining the Impact of Immune Dysregulation on CD4 T Cell Responses to HIV-1 and SARS-COV-2, Jacob K. Files

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Transcriptional Regulation of Metabolism and Synaptic Function in Neurons, Stephanie N. Fox

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Understanding the Protumorigenic Functions of ST6GAL1 in Glioblastoma Stemness and Metabolism, Sajina GC

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Characterizing the Role of Tissue-Specific Retinol Dehydrogenases, Kelli Rae Goggans

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Cell Type-Specific Diurnal Variation in Hippocampus Physiology, Lacy Kathryn Goode

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Epigenetic Regulation of Gene Expression in Temporal Lobe Epilepsy, Rebecca Mary Hauser

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Restoring the Sphingolipid Balance in Glioblastoma, Cyntanna C. Hawkins

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Three Heads are Better Than One: A Structural Look at Staphylococcal Bacteriophage Capsids, N'Toia Chivon Hawkins