ETDs from Heersink School of Medicine

ETDs from Heersink School of Medicine

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2023

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Challenges and Opportunities in Glioblastoma and Immunovirotherapy with Oncolytic Herpes Simplex Virus Type 1, Dagoberto Estevez-Ordonez

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Application of Machine Learning and Network Approaches to Prioritize Safe and Efficacious Drug Repurposing Candidates, Jennifer L. Fisher

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Molecular Influences of Racial Disparities in Pancreatic Neuroendocrine Tumors, Brendon Herring

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Molecular Determinants of Retroviral Gag Targeting to the Plasma Membrane for Assembly, Dominik Herrmann

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Unveiling the Molecular Features of Cancer Health Differences Through Multi-Omics Data Analysis, Fengyuan Huang

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Investigating Regulatory Mechanisms of Transcription by RNA Polymerase I, Abigail Kate Huffines

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The Long Non-Coding RNA NEAT1 Mediates Astrocyte Gene Expression and Hippocampus-Dependent Memory in Aging and Alzheimer's Disease, Ashleigh Burns Irwin

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Biochemical Characterization of RNA Polymerases I, II, and III and Its Therapeutic Implications, Ruth Qian Jacobs

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Understanding Molecular Mechanisms of Glioblastoama Resistance to Design Novel Combinatorial Therapies, Amber B. Jones

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Impact Of Exercise On Antioxidative-Stress Induced Endoplasmic Reticulum Dysfunction And Cardiac Remodelling, Arun Jyothidasan

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Optimization of Progranulin Gene Therapy, a Potential Treatment for Frontotemporal Dementia, Shreya Natesh Kashyap

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The Critical Period Of Long-Term Plasticity In Adult-Born Granule Cells Is Mediated By T-Type Calcium Channels, William Michael Kennedy

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The Molecular and Structural Basis of B Cell Epitope Targeting in Transplant Rejection, John T. Killian Jr

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Characterizing The Role Of Mapk Phosphatases In Age-Dependent Macrophage Dysfucntion And Increased Suceptiblity To Pneumonia In A Tnf-Dependent Manner, Katherine Lauren Kruckow

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Plasticity Characteristics of CXCR5+ CD4+ T Memory Cells and CXCR5- Non-TFH Memory Cells, Ching-En Lee

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Structural Characterization of Autoreactive IgG Fabs in the Context of IgA Nephropathy, Jordan Lingo

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Time-Restricted Feeding Attenuates Obesity-Induced Muscle Dysfunction Through Energy Metabolism And Microbiota Modulation, Chris Livelo

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Time-Restricted Feeding Modulates Dgat2 Expression In Cardiac And Skeletal Muscle, Yiming Guo Livelo

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Molecular imaging to evaluate tumor heterogeneity and guide treatment of breast cancer, Yun Lu

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Molecular Mechanisms of Amphetamine Abuse, Samuel James Mabry

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Investigating the Effects of Immune Checkpoint Inhibition and Combined Treatment with Evofosfamide on the Tumor Microenvironment Through Hypoxia Imaging, Kaytlyn Carter McNeal

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Early Life Stress and Endothelin Receptor Type A: Separate Roles in Mediating Colitis, Rachel Q. Muir

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Imaging Nanoscale Plasma Membrane Dynamics Reveals Diversity in Clathrin-Coated Vesicle Formation, Tomasz Jacek Nawara

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Manipulation and Dependence on Host Cell Cycle by Human RNA and DNA Viruses: Human Coronavirus OC43 and BK Polyomavirus, Jason M. Needham

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Chronic HIV Infection Influences the Immune Response to SARS-COV-2, Skye Opsteen

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Cd151+ T Cell Frequencies As An Immunological Clock That Identifies Premature Immunological Aging In People With Hiv, Mildred Perez

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A Tale of Two Waves: The Role of Genomic Enhancers in Regulating Transcriptional and Epigenetic Responses to Neuronal Activitiy, Robert A. Phillips III

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Understanding the Dual Role of the Oncolytic Viruses and Natural Killer Cells in Targeting Neuroblastoma, Colin Harrington Quinn

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T-BET Regulates the Maintenance and ASC Differentiation Potential of the Lymph Node and Lung Memory B Cell Compartments, Christopher A. Risley

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CIS-Regulatory Elements: Relevance for Alzheimer's Disease, Brianne Brazell Rogers

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Investigating The Electrostatics Of Mucins As Key Contributors To Mucus Stasis In Cystic Fibrosis, Elex Skylar Rose

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Transcriptional Regulation in Early Stage CD4+ T Cell Activation and Differentiation, Andrew Ray Schroeder

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The Effects of Cannabidiol on Brain Temperature in Treatment-Resistant Epilepsy, Ayushe A. Sharma

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Expression of ST6GAL1 Imparts Stem-Like Cell Behaviors, Thereby Promoting Neoplasia, Sejal Sanjay Shinde

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Exercise-Driven Epigenetic and Transcriptomic Changes in an Experimental Model of Temporal Lobe Epilepsy, Silvienne C. Sint Jago

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The Influence Of Proximity On Patient Outcomes For Differently Structured Ambulatory Surgery Centers, Wendy Michelle Smith

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Interactions Between Pseudomonas Aeruginosa and the Oral Commensal Streptococcus Salivarius, Sara Noelle Stoner

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Sex-Stratified Genetic Analysis of Gout and Comorbidities, Nicholas Andrew Sumpter

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Neuropeptide Y Overexpression In The Presence Of P23H Rhodopsin Mutation, Jean Sun

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Aberrant Signal Transduction of Neuronal Injury: Trauma and Toxicology, Alan Umfress

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Investigating the p53 Tumor-Suppressive Network and the Dynamics/Mechanism of p53 Loss of Heterozygosity, Jun Wang

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Select Lipid Signaling. Derived From T-Cells Is An Important Contributor To Type 1 Diabetes Development, Tayleur White

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The Role of Tissue- and Cell-type-specific Expression and Regulation in SETBP1-associated Diseases, Jordan Hailey Whitlock

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Regulating Cancer Cell Metabolism During Hypoxia-Reoxygenation: Examing the Interplay of Gasotransmitters and Glutaminolysis, Dianna L. Xing

Theses/Dissertations from 2022

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Distinct Clinical Manifestations Associated with Autoantibodies and Cytokines in Systemic Lupus Erythematosus, Fatima K. Alduraibi

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Elucidating the Role of STAT4 in CD4 T Cell Mediated Pathogenicity, Ashlyn E. Anderson

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The Role of the Bone Marrow Microenvironment in FLT3-ITD Acute Myeloid Leukemia Stem Cell Resistance to FLT3 Inhibition, Nicholas R. Anderson

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Induction of Antibiotic Activity Against Methicillin-Resistant Staphylococcus Aureus in Small Molecules Through Zinc Activation, Rachel Michaela Andrews

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Molecular and Cellular Mechanisms of Resistance Training-Induced Skeletal Muscle Hypertrophic Response Heterogeneity in Older Adults, Margaret Bell

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NOX2-Derived Superoxide and MDA5-Dependant Responses Contribute to Autoimmune Diabetes, Samuel Isaac Blum