Heersink School of Medicine ETDs

Heersink School of Medicine ETDs

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2022

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Hedgehog Signaling Rewires M2 Macrophage and Regulatory T Cell Metabolism Within the Tumor Microenvironment of Breast Cancer, Dominique C. Hinshaw

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A Gastrointestinal-Specific Antibiotic as an Experimental Treatment for Anxio-Depressive Disorders, Yuang-Tai Huang

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Elucidating PGC-1α and ERRγ Gene Regulation in Neurons, Kathlene Lanphear Joyce

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The Role of Protein Translation and Degradation in Aging and Alzheimer Disease Pathogenesis, Harper S. Kim

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Driving Anger and Aggression in Persons With and Without ADHD, Maria T. Lechtreck

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Impact of Nontypeable Haemophilus Influenzae and Pseudo Aeruginosa Polymicrobial Infections on the Cystic Fibrosis Lung, Natalie R. Lindgren

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Roles of Chemokine Receptors in T Cell Accmulation in Omental Tumors, Mingyong Liu

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Primary Cilia Regulate Inflammation and Macrophage Accumulation During Injury and Cyst Formation in Mouse PKD Models, Zhang Li

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Early Life Stress and Barrier Dysfunction of the Blood-Brain Barrier, Margaret Ellen Lloyd

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Study of the Effects of Contusion Spinal Cord Injury and Optogenetic Stimulation on Lower Urinary Tract Function, Salvador A. Lopez

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Tissue Engineered Cardiac Muscle Patches with Human Pluripotent Stem Cells Enhance the Repairing Efficacy of Infarcted Cardiac Muscle in Mouse Model, Xi Lou

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Regulation of Stromal Cells Through Inflammatory Signalling, Victoria Matkins

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Synergy Between Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa During Polymicrobial Airway Infections, Melissa Skye McDaniel

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Analysing the Structural Dynamics of Retinoid X Receptor Using Hydrogen Deuterium Exchange Mass Spectrometry, Nathalia Melo

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The Roles of Repressive and Activating Epigenetic Factors in Vertebrates Neural and Neural Crest Development, Saeid Mohammad Parast

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Disease and Diet-Induced Disruption of Effector T Cell Homeostasis, Patrick Axel Molina

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The Identification and Phenotypic Characterization of Circulating Flagellin Antigen-Specific CD4+ T Cells in Crohn's Disease Patients, Nadine N. Morgan

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Molecular Imaging of Cancer for Detection and Monitoring of Response to Combination Therapy, Tiara S. Napier

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Effeccts of HIV-1 Tat on TSPO, a Biomarker of Neuroinflammation, Nguyen Thuy Nhu Nguyen

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Effects of Exercise on Cerebral Oxygen Extraction Fraction, Hippocampal Subfields, and Cognition in Older Women, Amani M. Norling

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Characterization of the Phenotype and Functional Properties of Myeloid Subpopulations in Chronic Inflammatory Conditions, Krystla Leandra Ong

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Applying PET Imaging to Cancer Immunotherapy to Improve Clinical Outcomes, Kirsten M. Reeves

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The Role of DOCK3 In Normal Skeletal Muscle Function and Metabolism, Adrienne Samani

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Targeting the Frataxin Transcriptional Defect as a Therapeutic Approach for Friedreich's Ataxia, Anna Maria Schreiber

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Molecular Mechanism and Impact of SOX2 Regulation by the Transforming Growth Factor-ß Members in Ovarian Cancer Survival and Metastasis, Zainab Shonibare

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The Role of Nitric Oxide and Cyclic Guanosine Monophosphate Signaling in Arteriovenous Fistula Maturation, Maheshika S. Somarathna

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Study of Microrna-23A Cluster in Bone Formation, Revati Suryawanshi

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The Requirement of Transcriptional Lim Complex Co-Regulators for Pancreatic Endocrine Cell Development and Function, Eliana Davi Toren

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Alterations in Synaptic Structure and Tau Phosphorylation in Alheimer's Disease, Courtney K. Walker

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Epigenetic Regulation by O-GlcNAc Alters Anti-Fibrotic Gene Expression in IPF Fibroblasts, Qiuming Wu

Theses/Dissertations from 2021

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Characterization of RNA Polymerase I Trigger Loop Mutations, Collin Ainslie

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A Novel In Vitro Model To Study Immune Interactions In Glioblastoma, Hasan Alrefai

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The Pathomechanistic Role of Neuropeptide Y in the Skin: Overexpression of NPY Induces Chronic Inflammation and Skin Pathology, Zoya Tatiana Anderson

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Suppressing Islet Graft Rejection With Antioxidant-Based Encapsulation Materials, Jessie Marie Barra

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Structural changes to desmosomal architecture during assembly and maturation, Reena R. Beggs

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Novel Roles For Classic And Predicted Cilia Genes, Melissa Bentley

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The Impact Posttraumatic Stress Disorde on the Developing Brain and Educational Considerations, Kristen N. Buford

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Characterization of Cellular and Viral Factors that Define the Stability of the Latent HIV-1 Reservoir, Eric Carlin

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Production and Purification of Titanium-45 for Imaging of PSMA+ Prostate Cancer, Ivis Francis Chaple

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TGFβ Provides the Backbone of Embryogenesis: Elucidating the Role of TGFβ Signaling and its Downstream Effectors on Spinal Column Development, Sade Williams Clayton

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Stress And Neuropeptide Y: Hippocampal Crossroads, Mariana Andrea Cortes

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Hyperphosphatemia Contributes To Functional Iron Deficiency And Skeletal Muscle Wasting, Brian Anthony Czaya

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Targeting Oncogenic microRNA in Lung Cancer, Mackenzie Lauren Davenport

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Use-Dependent, Post-Critical Period Structural Plasticity in Primary Visual Cortex Following Central Vision Loss, Matthew Defenderfer

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The HOCl response of Escherichia coli., Rhea Marie Derke

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The Impact of Blimp1 on eTreg Stability and the Tumor Microenvironment, Michael Dixon

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Regulation of Nitric Oxide Syntahse 3 By Histone Deacetylase, Luke S. Dunaway

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Experience-Dependent Plasticitiy of Functional Connectivity in Human Visual Cortex Following Central Vision Loss, Leland Lanelle Fleming

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Diurnal Variation in Hippocampal Neurophysiology and Pathophysiology, Allison R. Fusilier

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Upregulation Of Somatostatin Receptor 2 In Neuroendocrine Tumors Using Histone Deacetylase Inhibitors, Rachael Elizabeth Guenter