ETDs from Heersink School of Medicine

ETDs from Heersink School of Medicine

 
Electronic versions of theses and dissertations from graduates of the School of Medicine, University of Alabama at Birmingham.

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Theses/Dissertations from 2022

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Defining Genetic Underpinnings of Cellular Diversity and Vulnerability in the Context of Parkinson's Disease, Stephanie M. Boas

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The Role of Mitochondrial Genetic Background in Cellular Function, Response to Cell Stress and Disease Susceptability, Jamelle A. Brown

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IL-22 Mediated Host Defense During Attaching-Effacing Pathogen Infection, Baiyi Cai

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Grainyhead-Like 2 (GRHL2) Has Anti-Oncogenic Potential in Glioblastoma, Rachel M. Carnes

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Comprehensive Characterization of Structural Variations Using Long-Read Sequencing Data, Yu Chen

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The Role of Complement C3 in IgA Nephropathy, Sarah Elizabeth Coffee

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IL-2-Mediated STAT3 Activation Controls Effector T Regulatory Cell Development, Emma C. Dean

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Integrated Phenotypic and Molecular Expression Circuits in End-Stage Osteoarthritis, Devin J. Drummer

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Determining the Impact of Immune Dysregulation on CD4 T Cell Responses to HIV-1 and SARS-COV-2, Jacob K. Files

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Transcriptional Regulation of Metabolism and Synaptic Function in Neurons, Stephanie N. Fox

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Understanding the Protumorigenic Functions of ST6GAL1 in Glioblastoma Stemness and Metabolism, Sajina GC

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Characterizing the Role of Tissue-Specific Retinol Dehydrogenases, Kelli Rae Goggans

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Cell Type-Specific Diurnal Variation in Hippocampus Physiology, Lacy Kathryn Goode

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Epigenetic Regulation of Gene Expression in Temporal Lobe Epilepsy, Rebecca Mary Hauser

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Restoring the Sphingolipid Balance in Glioblastoma, Cyntanna C. Hawkins

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Three Heads are Better Than One: A Structural Look at Staphylococcal Bacteriophage Capsids, N'Toia Chivon Hawkins

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Hedgehog Signaling Rewires M2 Macrophage and Regulatory T Cell Metabolism Within the Tumor Microenvironment of Breast Cancer, Dominique C. Hinshaw

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A Gastrointestinal-Specific Antibiotic as an Experimental Treatment for Anxio-Depressive Disorders, Yuang-Tai Huang

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Elucidating PGC-1α and ERRγ Gene Regulation in Neurons, Kathlene Lanphear Joyce

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The Role of Protein Translation and Degradation in Aging and Alzheimer Disease Pathogenesis, Harper S. Kim

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Driving Anger and Aggression in Persons With and Without ADHD, Maria T. Lechtreck

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Impact of Nontypeable Haemophilus Influenzae and Pseudo Aeruginosa Polymicrobial Infections on the Cystic Fibrosis Lung, Natalie R. Lindgren

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Roles of Chemokine Receptors in T Cell Accmulation in Omental Tumors, Mingyong Liu

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Primary Cilia Regulate Inflammation and Macrophage Accumulation During Injury and Cyst Formation in Mouse PKD Models, Zhang Li

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Study of the Effects of Contusion Spinal Cord Injury and Optogenetic Stimulation on Lower Urinary Tract Function, Salvador A. Lopez

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Regulation of Stromal Cells Through Inflammatory Signalling, Victoria Matkins

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Synergy Between Stenotrophomonas Maltophilia and Pseudomonas Aeruginosa During Polymicrobial Airway Infections, Melissa Skye McDaniel

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Analysing the Structural Dynamics of Retinoid X Receptor Using Hydrogen Deuterium Exchange Mass Spectrometry, Nathalia Melo

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The Roles of Repressive and Activating Epigenetic Factors in Vertebrates Neural and Neural Crest Development, Saeid Mohammad Parast

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Disease and Diet-Induced Disruption of Effector T Cell Homeostasis, Patrick Axel Molina

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The Identification and Phenotypic Characterization of Circulating Flagellin Antigen-Specific CD4+ T Cells in Crohn's Disease Patients, Nadine N. Morgan

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Molecular Imaging of Cancer for Detection and Monitoring of Response to Combination Therapy, Tiara S. Napier

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Effects of Exercise on Cerebral Oxygen Extraction Fraction, Hippocampal Subfields, and Cognition in Older Women, Amani M. Norling

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Characterization of the Phenotype and Functional Properties of Myeloid Subpopulations in Chronic Inflammatory Conditions, Krystle Leandra Ong

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Applying PET Imaging to Cancer Immunotherapy to Improve Clinical Outcomes, Kirsten M. Reeves

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The Role of DOCK3 In Normal Skeletal Muscle Function and Metabolism, Adrienne Samani

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Targeting the Frataxin Transcriptional Defect as a Therapeutic Approach for Friedreich's Ataxia, Anna Maria Schreiber

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Molecular Mechanism and Impact of SOX2 Regulation by the Transforming Growth Factor-ß Members in Ovarian Cancer Survival and Metastasis, Zainab Shonibare

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The Role of Nitric Oxide and Cyclic Guanosine Monophosphate Signaling in Arteriovenous Fistula Maturation, Maheshika S. Somarathna

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Study of Microrna-23A Cluster in Bone Formation, Revati Suryawanshi

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The Requirement of Transcriptional Lim Complex Co-Regulators for Pancreatic Endocrine Cell Development and Function, Eliana Davi Toren

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Alterations in Synaptic Structure and Tau Phosphorylation in Alheimer's Disease, Courtney K. Walker

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Epigenetic Regulation by O-GlcNAc Alters Anti-Fibrotic Gene Expression in IPF Fibroblasts, Qiuming Wu

Theses/Dissertations from 2021

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Characterization of RNA Polymerase I Trigger Loop Mutations, Collin Ainslie

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A Novel In Vitro Model To Study Immune Interactions In Glioblastoma, Hasan Alrefai

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The Pathomechanistic Role of Neuropeptide Y in the Skin: Overexpression of NPY Induces Chronic Inflammation and Skin Pathology, Zoya Tatiana Anderson

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Suppressing Islet Graft Rejection With Antioxidant-Based Encapsulation Materials, Jessie Marie Barra

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Structural changes to desmosomal architecture during assembly and maturation, Reena R. Beggs

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Novel Roles For Classic And Predicted Cilia Genes, Melissa Bentley

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Characterization of Cellular and Viral Factors that Define the Stability of the Latent HIV-1 Reservoir, Eric Carlin